By Merrick Moseley BSc PhD, Alistair Fielder MD

ISBN-10: 0750646918

ISBN-13: 9780750646918

This booklet offers a precis and synthesis of present concerns and learn in the box of 1 of the main difficult paediatric eye stipulations - Amblyopia.

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Extra resources for Amblyopia: A Multidisciplinary Approach, 1e

Example text

In comparison with the responses driven by the normal eye, those driven by the amblyopic eye were always depressed. Barnes and co-workers concluded that area VI is dysfunctional in human amblyopia. Visual evoked potential There have of course been numerous visual evoked potential (VEP) studies showing evidence of cortical dysfunction in amblyopia, several claiming that area VI is affected (see Regan, 1989, for a review). However, as already noted, attempts to determine the site of dysfunction with electrical measures of brain activity are notoriously difficult.

Anisometropic (half-filled symbols) amblyopes (from Hess and Pointer, 1985). 40 Amblyopia: A Multidisciplinary Approach contrast sensitivity deficit, which does not lie at the heart of the amblyopes perceptual disability. In general, the animal models have come to two main conclusions: there is no difference between strabismic and non-strabismic anisometropic amblyopia, and the sole deficit in amblyopia is contrast sensitivity (see Kiorpes and McKee, 1999). Both of these conclusions are at odds with the bulk of the psychophysics of human amblyopia as outlined in this chapter.

If it depends on top-down influences, then the deficit in amblyopia may implicate the extensive feedback pathways from extra-striate to striate cortex, rather than the traditional feed-forward ones. 18 Results for contour detection in a group of strabismic amblyopes. Percent correct contour detection is plotted against the contour curvature for the normal (unfilled circles symbols) and fel/ow amblyopic eye (filled circles symbols). , 1997). 38 Amblyopia: A Multidisciplinary Approach AT LEAST TWO TYPES OF AMBLYOPIA We generally talk about amblyopia as a single entity, but there is now ample evidence to suggest that strabismic and non-strabismic forms may be different.

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Amblyopia: A Multidisciplinary Approach, 1e by Merrick Moseley BSc PhD, Alistair Fielder MD

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