By James R. Swearengen

ISBN-10: 0849328365

ISBN-13: 9780849328367

The significance connected to swiftly constructing our biodefensive functions has lately ended in a considerably elevated investment for biodefense learn. therefore, researchers will reply with an attempt equivalent to the problem, generating a powerful physique of findings.

To make sure that this attempt maintains within the most productive demeanour, Biodefense: examine technique and Animal versions offers a radical old and present evaluate of biodefense examine, encouraging researchers to leverage appropriate effects, instead of reproduction them. through development at the paintings of others, scientists might be in a position to continue in a fashion that makes the simplest use of accessible assets, whereas fending off pointless duplication of animal learn.

Including contributions from well-known leaders within the box who've constructed and subtle the animal types provided, this ebook examines these bacterial, viral, and poisonous brokers thought of to pose the best threats to public defense. every one part on a selected agent offers pertinent heritage details, through an outline of these animal types hired in study and trying out and a dialogue of the way the findings translate to human impression.

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Extra info for Biodefense: Research Methodology and Animal Models

Sample text

S. Biological Warfare program, with both offensive and defensive objectives. The first major objective of War Research Service was to develop defensive measures against possible biological weapons attack [8]. Under the guidance of Ira Baldwin, the Army Chemical Warfare Service (CWS) commenced operation of a large-scale research and development program, and the facility at Camp Detrick was the first of the laboratories and pilot plants to be constructed, starting in April 1943 [8,9]. Most of the serious infectious diseases regarded as biological warfare threats were natural diseases of agricultural animals that could also cause devastating illness in humans.

1 and 2, 1977. 9. , Cutting Edge: A History of Fort Detrick, Maryland 1943–1993. Headquarters, United States Army Garrison, Public Affairs Office, Fort Detrick, MD, 1993, 17–19. 10. , Beasts of the Earth: Animals, Humans and Disease, Rutgers University Press, New Brunswick, NJ, 2005. 11. , Handling of infectious agents. J. Am. Vet. Med. Assoc. 161, 1557, 1972. 12. , History of chemical and biological warfare: an American perspective, in Textbook of Military Medicine: Medical Aspects of Chemical and Biological Warfare, Office of the Surgeon General, Department of the Army, Washington, DC, 1989, 9.

Limitation on use of humans as experimental subjects, 1972. 27. National Research Act (Pub. L. 93-348) of July 12, 1974 28. Army Regulation 70-25, Research and development: use of volunteers as subjects of research, July 31, 1974. 29. Memorandum of understanding between the Food and Drug Administration and the Department of Defense concerning investigational use of drugs by the Department of Defense, October 24, 1974. 30. The Belmont report, ethical principles and guidelines for the protection of human subjects in research, The National Commission for the Protection of Human Subjects, April 18, 1979.

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Biodefense: Research Methodology and Animal Models by James R. Swearengen


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