By Norbert Schrage, François Burgher, Jöel Blomet, Lucien Bodson, Max Gerard, Alan Hall, Patrice Josset, Laurence Mathieu, Harold Merle
More than 25,000 chemical items have the capability to reason ocular burns. simply because such burns can lead to lack of sight or the necessity for corneal transplantation, they need to be taken very heavily. This booklet is the 1st to be dedicated solely to chemical ocular burns. All elements of the topic are lined, together with heritage, epidemiology, chemical brokers and reactions, histology, pathophysiology, scientific symptoms, clinical and surgical remedies, and emergency care. specific realization is paid to the mechanisms inquisitive about ocular burns and to the hyperlinks among the chemical reactivity of corrosive brokers and the medical manifestations. present ideas of decontamination are absolutely defined and the most recent therapy concepts are mentioned intimately. This publication stands on the interface of the chemical and scientific sciences. it will likely be of significant functional worth to ophthalmologists and medical professionals in emergency clinical and burns devices, and may acquaint chemists with the scientific effects of corrosivity.
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Additional info for Chemical Ocular Burns: New Understanding and Treatments
7. But, for us, everything is naturally molecular chemistry in an ultrastructural scale. This mechanistic and materialistic approach might surprise any doctor? Nevertheless not only this molecular organization of the living substance is real but it even helps to understand the intimacy of the eye chemical danger and the ultimate consequences of chemical burns. The living substance is constituted by six major atomic elements entering the architecture of the biochemical molecules. They are carbon, which defines the organic chemistry (that is the chemistry of what’s alive), hydrogen, oxygen, nitrogen, phosphorus, and sulfur.
8). A molecule is said to be protic when it can release a proton. The connection between the hydrogen and another atom is weak enough. A molecule that cannot release a proton is O CH3 H3C C O Acetone Propan-2-one The partition coefficient of solvents is also a reactional energy scale. A substance has more or less of affinity and it thus dissolves more easily in a type of solvent than in the other one. 11 Solvent’s partition coefficient that measures the proportion of the substance within each of both phases proposed.
In April 2010 the CAS registered, in all, more than 61 million substances. Among these, more than 25,000 irritant and corrosive chemicals were identified as having the potential to cause burns . In Europe, 100,204 commercial chemical substances have been recognized and numbered under EINECS (European INventory of Existing Commercial chemical Substances) by the European Chemical Bureau (ECB) System. Another 4,381 “new” substances are classified under ELINCS Information System (European LIst of Notified Chemical Substances) since May 11, 1981.
Chemical Ocular Burns: New Understanding and Treatments by Norbert Schrage, François Burgher, Jöel Blomet, Lucien Bodson, Max Gerard, Alan Hall, Patrice Josset, Laurence Mathieu, Harold Merle