By M.J. Elder, W. Bernauer, J.K.G. Dart, F. Bandello
Cicatrizing conjunctivitis is without doubt one of the such a lot not easy explanations of ocular floor sickness at the present time, and with no applicable intervention, corneal blindness or lack of sight from supervening an infection is usual. simply because lots of those illnesses are infrequent, there's usually restricted administration event to be had and the assets for study into remedy and pathogenesis might be scarce. this article summarizes current therapy innovations and the medical and laboratory experiences validating those techniques. themes mentioned comprise an in-depth examine non-progressive motives together with trachoma, Stevens-Johnson syndrome and ligneous conjunctivitis. The textual content additionally examines continual revolutionary conjunctival cicatrization, the ailments which reason it, their medical and laboratory evaluate, immunopathogenesis, sequelae and administration. it may relief the making plans of intervention and remedy of a bunch of ailments formerly linked to terrible analysis.
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Extra resources for Cicatrising Conjunctivitis (Developments in Ophthalmology)
Hidayat AA, Riddle PJ: Ligneous conjunctivitis. A clinicopathologic study of 17 cases. Ophthalmology 1987;94:949–959. Firat T: Ligneous conjunctivitis. Am J Ophthalmol 1974;78:679–688. De Cock R, Ficker LA, Dart JG, Garner A, Wright P: Topical heparin in the treatment of ligneous conjunctivitis. Ophthalmology 1995;102:1654–1659. Weinstock SM, Kielar RA: Bulbar ligneous conjunctivitis after pterygium removal in an elderly man. Am J Ophthalmol 1975;79:913–915. Girard LJ, Veselinovic A, Font RL: Ligneous conjunctivitis after pingueculum removal in an adult.
Trachomatis infection and hsp60 remains the most likely candidate antigen for generating the major immunopathic response. Immune responses to chlamydial hsp60 are correlated with disease sequelae in humans and seem to be genetically controlled in part by genes in Daniell/Taylor 16 Table 1. 5 mm in size) on the central upper tarsal conjunctiva TI, trachomatous inflammation, intense: inflammatory thickening of the upper tarsal conjunctiva with more than 50% of deep tarsal vessels obscured. TS, trachomatous scarring: presence of easily visible scarring in the upper tarsal conjunctiva TT, trachomatous trichiasis: presence of at least one eyelash rubbing the eyeball CO, corneal opacity: presence of easily visible central corneal opacity, sufficiently dense to obscure the pupil margin (thought to be consistent with a visual acuity of 6/18 or less) the MHC locus.
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Cicatrising Conjunctivitis (Developments in Ophthalmology) by M.J. Elder, W. Bernauer, J.K.G. Dart, F. Bandello